What is Homo sildenafil CAS 642928-07-2 ?
What is Homo sildenafil CAS 642928-07-2 ?
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Homo Sildenafil (also known as methyl-sildenafil) is a synthetic drug which acts as a phosphodiesterase inhibitor. It is an analog of sildenafil and vardenafil. Homo Sildenafil is a new analog of Sildenafil (sc-338584). Sildenafil is a selective inhibitor of the type 5 cGMP phosphodiesterase (PDE5 inhibitor) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism.
Homosildenafil Specifications
Product Name
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Homo Sildenafil
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Chemical Name
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5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one;Homo Sildenafil
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Brand Name
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Methyl-sildenafil
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Drug Class
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PHOSPHODIESTERASE TYPE-5 INHIBITOR
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CAS Number
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642928-07-2
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InChIKey
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MJEXYQIZUOHDGY-UHFFFAOYSA-N
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Molecular Formula
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C23H32N6O4S
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Molecular Weight
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488.607 g/mol
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Monoisotopic Mass
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488.221 g/mol
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Melting Point
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200-202°C
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Freezing Point
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192-194°C
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Biological Half-Life
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4 hours
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Color
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White Solid
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Solubility
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Chloroform (Slightly), Methanol (Slightly, Heated)
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Storage Temperature
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-20°C Freezer
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Application
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Homo sildenafil is a new analog of Sildenafil, which is an orally active selective type 5 cGMP phosphodiesterase inhibitor.
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